Albendazole tablets p/o 200mg №2x1

Albendazole Tablets 200mg: Effective Treatment for Intestinal & Systemic Helminth Infections

Albendazole 200mg tablets are a highly effective medication for treating a wide range of intestinal and systemic helminth (worm) infections. This comprehensive guide provides information on its uses, dosage, precautions, and potential side effects.

Indications for Use:

Intestinal Infections:

• Nematodoses: Ascariasis, enterobiasis, trichuriasis, ankylostomiasis, necatoriasis, strongyloidiasis.
• Trematodosis: Opisthorchiasis and clonorchiasis.
• Giardiasis: In children aged 2-12 years.
• Cestodoses: Taeniasis (Taenia solium, Taenia saginata), hymenolepiasis

Systemic Helminthiases:

• Echinococcosis: Albendazole is particularly effective for treating cysts in the liver, lungs, and peritoneum.
• Cystic echinococcosis (caused by Echinococcus granulosus): Used for inoperable cases, pre-operative treatment, post-operative management, and after percutaneous cyst drainage.
• Alveolar echinococcosis (caused by Echinococcus multilocularis): Treatment for inoperable disease, post-palliative surgery, and after radical surgery or liver transplantation.
• Neurocysticercosis: Used for patients with solitary or multiple brain cysts, arachnoid or intraventricular cysts, and grape-shaped cysts.

Dosage and Administration:

• Oral administration: Taken during meals, preferably at the same time each day.
• Dosage varies depending on the type of infection: See detailed dosage information below.
• For patients unable to swallow tablets whole: Crush the tablet and mix it with a small amount of water.

Dosage Information:

Intestinal Infections:

<table> <tr> <th>Infection</th> <th>Age</th> <th>Dosage</th> <th>Duration</th> </tr> <tr> <td>Enterobiasis, hookworm, necatoriasis, ascariasis, trichuriasis</td> <td>Adults & children > 2 years (>10 kg)</td> <td>400mg once daily</td> <td>Single dose</td> </tr> <tr> <td></td> <td>Children 1-2 years (>10 kg)</td> <td>200mg once daily</td> <td>Single dose</td> </tr> <tr> <td>Strongyloidiasis, taeniasis, hymenolepiasis</td> <td>Adults & children > 2 years (>10 kg)</td> <td>400mg once daily</td> <td>3 days (repeat after 2-3 weeks for hymenolepiasis)</td> </tr> <tr> <td>Clonorchiasis, opisthorchiasis</td> <td>Adults & children > 2 years (>10 kg)</td> <td>400mg twice daily</td> <td>3 days</td> </tr> <tr> <td>Larva Migrans skin syndrome</td> <td>Adults & children > 2 years (>10 kg)</td> <td>400mg once daily</td> <td>1-3 days</td> </tr> <tr> <td>Giardiasis</td> <td>Children 2-12 years</td> <td>400mg once daily</td> <td>5 days</td> </tr> </table>

Systemic Helminthiases:

<table> <tr> <th>Infection</th> <th>Duration</th> </tr> <tr> <td>Cystic echinococcosis</td> <td>28 days (repeat for inoperable cases, pre-operative treatment, and post-operative management)</td> </tr> <tr> <td>Alveolar echinococcosis</td> <td>28 days (repeat after 2 weeks)</td> </tr> <tr> <td>Neurocysticercosis</td> <td>7-31 days (repeat after 2 weeks)</td> </tr> </table>

Precautions:

• Liver Function: Monitor liver enzymes before each treatment cycle and every two weeks during treatment. Discontinue albendazole if liver enzyme levels increase by two times or more.
• Bone Marrow Suppression: Monitor blood counts before and every two weeks during treatment.
• Neurocysticercosis: Patients may experience neurological symptoms due to an inflammatory response. Start corticosteroid and anticonvulsant therapy immediately if these symptoms occur.
• Pregnancy and Lactation: Albendazole is contraindicated during pregnancy. Women of childbearing age should receive a negative pregnancy test before treatment. It is not known if albendazole is secreted in breast milk, so it should not be used during breastfeeding.
• Other Precautions: Consult a doctor before taking albendazole if you have any pre-existing conditions, such as liver disease or impaired renal function.

Possible Side Effects:

Common:

Headache, dizziness, nausea, vomiting, abdominal pain.

Uncommon:

Increased liver enzymes, rash, itching, urticaria, alopecia (hair thinning).

Rare:

Pancytopenia, aplastic anemia, agranulocytosis, leukopenia, Stevens-Johnson syndrome.

Overdose:

There is no specific antidote. Symptoms are not described. Seek immediate medical attention if suspected overdose occurs.

Storage:

Store in a dry, cool, and dark place. Keep out of reach of children.

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Note: This is a sample guide. Please consult a healthcare professional for proper diagnosis, treatment, and dosage recommendations. **Self-treating can be dangerous. Always follow your doctor's advice and instructions.**