AndroDoz Capsules 60 Count (503mg)

AndroDoz Capsules 503 mg, 60 pcs

Description: AndroDoz is a dietary supplement providing a balanced combination of 9 active ingredients that improve semen quality by addressing various aspects of impaired spermatogenesis. This is particularly important given the multifactorial nature (multiple simultaneous causes) of male infertility.

Each daily dose (4 capsules of 503 mg) contains:

• L-arginine: 720 mg
• L-carnitine: 240 mg
• L-carnosine: 92 mg
• Coenzyme Q10: 10 mg
• Glycyrrhizic acid: 6 mg
• Zinc: 4.8 mg
• Vitamin E: 3.2 mg
• Vitamin A: 0.36 mg
• Selenium: 0.034 mg

Male infertility is a significant andrological issue, accounting for 30-50% of infertile marriages. Idiopathic infertility (unexplained infertility) constitutes a major cause of male infertility (up to 50%, according to large-scale international studies, including the Seven Countries Study).

Spermatogenesis, the complex multi-stage process of sperm production and maturation, lasting several weeks, is highly susceptible to negative influences. Idiopathic infertility is currently linked to impaired sperm antioxidant activity, resulting from deficiencies in amino acids, vitamins, micronutrients, coenzymes, and other essential bioactive components, along with external harmful factors (intoxication, overheating, poor environmental conditions, etc.).

When planning conception naturally, antioxidant supplements are recommended for 1-12 months (ideally starting 3 months before the intended conception and continuing until pregnancy). For assisted reproductive technologies (ART) like IVF and ICSI, to enhance procedure effectiveness, antioxidant complexes are recommended for 1 month (starting no later than 1 month before the procedure).

AndroDoz components exhibit synergy, meaning their combined effect is significantly stronger and achieved at much lower doses than when used individually.

Oxidative stress is a pathological cellular condition where cells are damaged by reactive oxygen species (free radicals). The negative impact of free radicals on male reproductive function is a critical concern. The simultaneous use of fat-soluble and water-soluble antioxidants is particularly promising for preventing oxidative stress and reducing its negative effects on spermatogenesis.

AndroDoz contains the most relevant antioxidants needed for spermatogenesis. This complex helps maintain the healthy state of the male reproductive system.

Individual Component Characteristics:

• L-carnitine: Concentrates in the epididymis and spermatozoa. This vitamin-like substance (vitamin B11 or vitamin T) energizes spermatogenesis and directly impacts male fertility. L-carnitine suppresses oxidative stress, crucial in idiopathic male infertility. It improves sperm motility and production.
• L-arginine: A bioactive isomer of the conditionally essential amino acid arginine. Seminal fluid proteins consist of up to 80% L-arginine, highlighting its importance in male reproductive health. Deficiency can lead to impaired spermatogenesis and infertility. L-arginine benefits prostate health and enhances spermatogenesis. It also regulates sexual function as a precursor to nitric oxide, supporting blood flow in male genitalia and improving erectile function.
• Coenzyme Q10 (Ubiquinone): Essential for synthesizing biochemical energy carriers. Effective for high physical exertion, increasing endurance. A potent antioxidant, it also restores the activity of other antioxidants, notably Vitamin E. Clinically proven synergy with L-carnitine contributes to increased sperm production and motility.
• L-carnosine: A natural component of human tissues and a potent water-soluble antioxidant. It enhances the effect of fat-soluble antioxidants like Vitamin E. It neutralizes heavy metals and prevents intoxication. L-carnosine protects the reproductive system, stimulates spermatogenesis, and improves sperm motility.
• Selenium (Selenium-enriched yeast): In its natural organic form, it has high bioavailability. An essential micronutrient involved in the entire life cycle, from conception to aging, and a component of various hormones and enzymes related to nearly all organs and systems. A potent antioxidant suppressing lipid oxidation and protecting cells from free radical damage. It protects spermatogenesis during acute and chronic intoxications. It synergistically interacts with Vitamins A and E, reducing their degradation and the body's need for them. Essential for normal male reproductive system function. Its organic form ensures gradual absorption, independent of vitamin levels, and maintains consistent blood plasma levels over time (creating a selenium depot).
• Glycyrrhiza glabra (Licorice): The roots and rhizomes contain glycyrrhizic acid and flavonoids, exhibiting antiviral, antifungal, anti-inflammatory, anti-allergic, immunomodulatory, and tonic effects. Glycyrrhizic acid inhibits thrombin (a component of the coagulation system present in semen involved in ejaculate thickening), possesses mucolytic action (thins mucus), and stimulates secretin production, which thins pancreatic duct, bile duct, and Brunner's gland secretions.
• Zinc Lactate: A highly bioavailable form of zinc. A vital micronutrient found in almost all body tissues. Essential for cellular respiration, oxygen utilization, genetic material reproduction (DNA and RNA), maintaining cell wall integrity, and neutralizing free radicals. Concentrated in the testes, epididymis, prostate, and semen. Crucial for the male reproductive system, initiating and maintaining testosterone production and activating spermatogenesis. It activates glutathione peroxidase, vital for sperm maturation and motility, and regulates spermoplama enzyme activity, influencing ejaculate coagulation and liquefaction. Zinc deficiency can cause infertility, delayed puberty, and reduced sexual function. Deficiency often occurs due to increased excretion caused by stress, electromagnetic radiation (computer work, prolonged TV exposure), toxins, heavy metals, pesticides, and other environmental pollutants. Biochemically interdependent with Vitamin A: Vitamin A promotes zinc absorption, and zinc is necessary for Vitamin A absorption. Simultaneous intake is relevant for male infertility and spermatogenesis anomalies due to infections, occupational hazards, and ionizing radiation.
• Vitamin E (Tocopherol): A key antioxidant, preventing cell wall damage by neutralizing hydrogen peroxide and other reactive oxygen species. Essential for new cell growth and immune system function. Reduces oxidative stress in testicular tissue, improves sperm motility, and enhances their ability to penetrate the egg cell. Synergizes with retinol and selenium.
• Vitamin A (Retinol): A crucial antioxidant protecting cell membranes from oxidation; influences protein synthesis and supports reproductive functions. Present in seminal fluid, it is necessary for spermatogenesis and sperm motility. Improves zinc absorption and enhances its antioxidant effect.

Clinical Studies:

Based on the results of the Multicenter Open-Label Study on the Efficacy and Safety of the Multicomponent Complex "AndroDoz," 2013*, the Open Comparative Study on the Efficacy and Safety of the Multicomponent Complex "AndroDoz" in Patients with Idiopathic Pathozoospermia, 2013**, and the Observational Study on the Efficacy and Safety of the "AndroDoz" Complex in Patients with Idiopathic Infertility, 2016***, AndroDoz:

• Improves sperm motility and the number of viable sperm.
• Reduces ejaculate viscosity.
• Influences increased testosterone levels.

AndroDoz can be used as a dietary supplement for:

• Decreased sperm motility and fertilizing capacity.
• Impaired male reproductive function.
• Preparation for assisted reproductive technologies in infertility treatment (IVF, ICSI).

*Participating Scientific Centers: [List of Centers – translated and formatted appropriately]

*** References for the studies (properly formatted).