Co-amlessa tablets 4mg/5mg/1.25mg 10x3

Co-Amlessa Tablets: A Comprehensive Guide to Dosage, Interactions, and Side Effects

Co-Amlessa tablets offer a fixed-dose combination of perindopril, indapamide, and amlodipine, all known to effectively control high blood pressure. This comprehensive guide provides essential information about dosage, interactions, and potential side effects, empowering you to make informed decisions about your health.

Understanding Co-Amlessa's Ingredients:

• Perindopril: An ACE inhibitor that relaxes blood vessels, lowering blood pressure.
• Indapamide: A diuretic that reduces fluid retention, further lowering blood pressure.
• Amlodipine: A calcium channel blocker that relaxes blood vessels, allowing for improved blood flow.

Co-Amlessa: A Powerful Solution for Hypertension:

• Combined action: This triple-action formula works synergistically, providing a comprehensive approach to managing hypertension.
• Convenient dosing: A single tablet offers a convenient way to receive all three medications, enhancing compliance.
• Tailored to individual needs: Available in different strengths, Co-Amlessa allows for personalized dosage adjustments.

Important Considerations Before Using Co-Amlessa:

• Renal impairment: Consult your doctor if you have moderate or severe kidney problems. Certain strengths may be contraindicated.
• Hepatic impairment: Co-Amlessa is contraindicated in severe liver dysfunction.
• Pregnancy and breastfeeding: Co-Amlessa is not recommended during pregnancy and breastfeeding due to potential risks to the developing fetus and infant.
• Lithium: Concomitant use with Co-Amlessa is generally not recommended due to potential lithium toxicity.

Potential Interactions with Other Medications:

• Aliskiren: Simultaneous administration is contraindicated.
• Potassium-sparing diuretics, potassium supplements: Increases the risk of hyperkalemia.
• Non-steroidal anti-inflammatory drugs (NSAIDs): May reduce the hypotensive effect of Co-Amlessa.
• Antidiabetic drugs (insulin, oral hypoglycemics): May increase the risk of hypoglycemia.
• Grapefruit juice: May enhance the hypotensive effect of Co-Amlessa.

Important Precautions and Potential Side Effects:

• Hypotension: Can occur, especially in patients with pre-existing low blood pressure or renal artery stenosis.
• Electrolyte disturbances: Hypokalemia and hyperkalemia are possible, requiring regular monitoring.
• Renal function: Co-Amlessa may impact renal function, requiring regular monitoring.
• Cough: Dry cough is a known side effect of ACE inhibitors.
• Angioedema: A serious allergic reaction that can affect the face, extremities, lips, tongue, pharynx, and larynx.

Dosage and Administration:

• Take as directed by your doctor: Individualized dosage and frequency are essential.
• One tablet per day: Usually taken in the morning, preferably before meals.

Remember: This information is for educational purposes only and does not substitute professional medical advice. Consult your doctor for personalized recommendations and to address any concerns or questions you may have about Co-Amlessa.

Keywords:

Co-Amlessa, perindopril, indapamide, amlodipine, hypertension, high blood pressure, dosage, interactions, side effects, precautions, renal impairment, hepatic impairment, pregnancy, breastfeeding, lithium, aliskiren, potassium, NSAIDs, antidiabetic drugs, grapefruit juice, hypotension, electrolyte disturbances, angioedema, cough.