Xian Shao: PMS & Menopause Relief (9-Pack)

Xiangshao Granules: Herbal Relief for PMS & Menopausal Symptoms (9 Packets)

Xiangshao Granules are a completely herbal remedy, a refined formula developed through extensive research and purification by Professor Zhang Zhenyu, the founder of emotional therapy in Traditional Chinese Medicine (TCM). This foundational treatment for women's emotional health offers significant efficacy and safety in managing the emotional and physical symptoms commonly associated with Premenstrual Syndrome (PMS) and menopause. It presents a novel, safe, and effective approach to treating women's emotional and somatic symptoms.

Pharmacological Action

Xiangshao Granules soothe the liver and regulate Qi, reduce swelling and alleviate pain, and aid in stomach regulation.

Indications & Symptoms

Premenstrual Syndrome (PMS):

Addresses Liver Qi stagnation. Symptoms include premenstrual irritability, breast tenderness, headaches, insomnia, vivid dreams, lower abdominal pain, bloating, nausea, vomiting, and more.

Menopausal Syndrome:

Targets Yin deficiency and Liver Yang hyperactivity. Symptoms include hot flashes, night sweats, irritability, insomnia, palpitations, pleuritic pain (rib pain), forgetfulness, dizziness, tinnitus, red tongue with a thin yellow coating, and a wiry or tense pulse.

Mechanism of Action & Scientific Backing

Xiangshao Granules demonstrably improve mood disorders through several key mechanisms:

• Enhanced GABAergic Neurotransmission: Significantly enhances GABABR2 regulation, effectively reducing anxiety and depression.
• Serotonergic Modulation: Regulates 5-HTR2c protein and mRNA expression, further combating anxiety and depression symptoms.
• Neurotrophic Factor Enhancement: Exhibits antidepressant effects by improving BDNF and TrkB levels in the hippocampus.
• Hypothalamic-Pituitary-Adrenal (HPA) Axis Regulation: Significantly lowers serum levels of CRH, CORT, and ACTH, contributing to its antidepressant action.

Clinical Studies

Multi-center, randomized, double-blind, placebo-controlled clinical trials have rigorously demonstrated the significant therapeutic effects of Xiangshao Granules on key symptoms such as mood disorders. Phase II and III clinical trials have confirmed the safety and efficacy of Xiangshao Granules, showing no negative impact on liver or kidney function. Minor gastrointestinal side effects such as abdominal pain and nausea were reported in a very small percentage of participants.

Dosage and Administration

Dissolve one sachet in warm boiled water:

• PMS: Take 1 sachet 3 times daily, starting 10 days before menstruation and continuing for 10 days. A two-menstrual-cycle course is recommended.
• Menopausal Syndrome: Take 1 sachet 3 times daily for an 8-week course.

Keywords: Xiangshao Granules, PMS, Premenstrual Syndrome, Menopause, Menopausal Symptoms, Hot Flashes, Night Sweats, Mood Swings, Anxiety, Depression, Traditional Chinese Medicine (TCM), Herbal Remedy, Liver Qi Stagnation, Yin Deficiency, Liver Yang Hyperactivity, Natural Remedy, Women's Health, Clinical Trials, GABA, Serotonin, BDNF, Hormonal Imbalance, Supplement.